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A-Level生物-应用遗传学Applied Genetics。

2016-08-29 09:58

来源:新东方整理

作者:上海新东方

Revision: Applied Genetics


Define genetic screening
Testing a population for the presence or absence of a gene

Discuss three advantages and disadvantages of genetic screening

Advantages

  • Lessen the devastating impact of genetic disease
  • Identification of persons who have genetically determined susceptibilities to specific environmental agents
  • Insurance Companies can give lower premiums

Disadvantage

  • Can stigmatize and emotionally traumatize those who learn that they are carriers of genetic defects
  • Invasion of privacy
  • Has the potential of being used to dictate who may or may not reproduce

State that the Human Genome project is an international cooperative venture to sequence the complete human genome

Discuss two possible advantages of this project

  • Understanding of many genetic diseases
  • Genome libraries
  • Production of gene probes to detect sufferers and carriers of genetic diseases
  •  Production of pharmaceuticals based on DNA sequences

Define clone
A group of organisms of identical genotype / a group of cells descended from a single parent cell.

Outline a technique used in the cloning of farm animals

  • Early division of a fertilized egg produces 8 cells each of which would give rise to an embryo (totipotency).
  • After in vitro fertilization processes the 8 resultant separated embryos can be transferred to surrogate mothers (e.g. cattle or sheep) to continue using selected prime animals for the production of gametes
  • At present used for genetically manipulated animals to produce pharmaceuticals

Discuss the ethical issues of cloning human embryos

  • Happens naturally in monozygotic twins
  • In vitro fertilization of twins unacceptable?
  • Selection of those fit to be cloned
  • Eugenics and super-race?

Discuss the results of crop plant and animal breeding

  • Breeding for disease resistance
  • Increased food production
  • Higher yields of milk/wool/protein
  • Breeding plants that can spread 

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